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Fibrin degradation product

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Principles of D-dimer testing

Fibrin degradation product (FDPs) are components of the blood produced by clot degeneration.[1] These are produced by the action of Plasmin on deposited fibrin.

The levels of these FDPs rises after any thrombotic event.

It can be used to test for disseminated intravascular coagulation.[2]

[edit] References

  1. ^ Gaffney PJ, Edgell T, Creighton-Kempsford LJ, Wheeler S, Tarelli E (1995). "Fibrin degradation product (FnDP) assays: analysis of standardization issues and target antigens in plasma". Br. J. Haematol. 90 (1): 187–94. doi:10.1111/j.1365-2141.1995.tb03399.x. PMID 7786784. 
  2. ^ Fibrin/Fibrinogen Degradation Products

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